How to Get the Best Results from GLP-1

September 25, 2025

GLP-1 medications (like semaglutide and tirzepatide) have changed the way we approach weight loss. They can be highly effective, but without the right clinical support, many patients run into frustrating—and preventable—problems:

  • Muscle loss (as much as 30–40% of total weight lost)
  • Weight loss plateaus due to metabolic slowdown
  • Nutrient depletion that impacts energy, mood, and recovery
  • Rebound weight gain after stopping the medication

At Confidia Health Institute, Dr. Kevin Greene and his team use a more advanced strategy. Instead of focusing only on weight loss, the goal is to preserve lean muscle, protect metabolism, and optimize long-term results.

This is what is called the GLP-1 Optimization Protocol.

The GLP-1 Optimization Protocol


Top-performing longevity clinics are helping patients achieve better, more sustainable results by pairing GLP-1 therapy with targeted cellular support.

The protocol is founded upon the following three fundamental pillars:


Results You Can Expect


  • Much less muscle loss compared to GLP-1 therapy alone
  • Fewer weight loss plateaus and continued fat reduction
  • Better weight maintenance after stopping GLP-1s
  • Higher energy, strength, and recovery throughout treatment


Patient-Friendly FAQ



  1. Why do people lose muscle on GLP-1 medications?
    Because these drugs reduce appetite, people often eat less protein and fewer nutrients. Combined with lower hydration, this leads to muscle breakdown unless it’s specifically supported.
  2. How does LeuSynergy™ help?
    It turns on cellular pathways that mimic the effects of exercise—protecting lean muscle while supporting fat loss.
  3. Isn’t regular hydration enough?
    Not always. GLP-1s reduce thirst, and plain water doesn’t always make it inside muscle cells. iCell Water™ pulls water into the cells, where it matters.
  4. What does AKG+™ do for weight loss?
    It helps your cells make energy more efficiently, reducing fatigue and supporting ongoing fat loss instead of plateaus.
  5. Do I need all three products?
    They work best together. Each one targets a different part of the problem—muscle, hydration, and metabolism. Together, they create a synergistic effect.

Take the Next Step with Confidia Health Institute


Dr. Greene and his team specialize in advanced, root-cause medicine—helping patients achieve weight loss that’s not only successful, but sustainable.

If you’re ready to go beyond simple weight loss and protect your muscle, metabolism, and long-term results, the GLP-1 Optimization Protocol is available through Dr. Kevin Greene and Confidia Health Institute.


👉 Ask Confidia Health Institute about the GLP-1 Optimization Protocol today—and discover how to transform weight loss into whole-body health optimization.